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Therefore, overall, our results agree with a predominantly anti-apoptotic role rather than an anti-ferroptotic role of NUPR1 in phBECs but at the same time underscore the known context- and cell type-specific nature of NUPR1-dependent protective mechanisms 47,64,66,67

The vitamin level in human body can be changed through dietary intake and drug supplementation, which also suggests that lowering VitB1 level or increasing VitB3 level in human body may provide new means and methods for clinical prevention and treatment of breast cancer