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Qu R, Ji Y, Ling Y, Ye C-Y, Yang S-M, Liu Y-Y, et al

Acknowledgements The author is grateful to the National Institutes of Health (R35GM142882) for support which enables investigations into halogenation biochemistry in the Agarwal laboratory

For more pronounced changes, such as significant skin brightening and the fading of hyperpigmentation, consistent treatment over three to six months is often required

The cost and availability of auto-antibodies testing, such as intrinsic factor and anti-parietal cell antibodies, can be a barrier to further investigation for vitamin B12 deficiency to exclude pernicious anemia