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The article provides an idea regarding the possible processes by which NAC treatment for COVID-19 may prevent infection-mediated abnormalities in male reproduction, and thus, it encourages in-depth studies in this field so that the clinical potencies of NAC as male reproductive ameliorator in SARS-CoV-2 infections are completely revealed

In hepatocytes, autophagy promotes lipid clearance (lipophagy) and reduces steatosis

The majority of patients had no meaningful weight loss or weight gain through maximum follow-up (Figure panel right)

After administration of M2-EVs into the joint of a CIA mouse model, the STMs polarization was significantly shifted from M1 to M2 phenotype in decreased joint swelling, arthritic index score and synovial inflammation, with corresponding reductions in bone erosion and articular cartilage damage (Kim et al., 2022a)