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also based on the Healthy Eating Plate) found that those who changed their eating behaviours had a statistically significant reduction in monthly migraine days (from 10 to less than 6) and a non-significant decrease in monthly painkiller intake (from approximately 12 to 8), with reductions in total carbohydrate, and red and processed meat consumption appearing to have the most pronounced benefit

At the molecular level, elevated circulating free fatty acids and aberrant cerebral lipid accumulation directly induce cerebrovascular endothelial dysfunction, ultimately compromising BBB integrity (82, 83)

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2019;52:e12627