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The proteins with most significant differences with a higher abundance in cases with progressive disease compared to non-progressive disease are listed in Table 7

At 48 h after the operation, mice were intravenously injected with LNP@AmB at a dose of 1 mg/kg amphotericin B every day for 5 days and images were obtained with a Lumina III Imaging System (PerkinElmer, USA) at 0 d, 3 d, and 6 d after treatment

In our study, FOXO4-DRI was found to effectively promote apoptosis in senescent cells by blocking the FOXO4-P53 interaction and facilitating P53 phosphorylation