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doi: 10.1016/j.urology.2015.07.026 107 MunceyWSellkeNKimTMishraKThirumavalavanNLoebA

Cytc binds to Apaf-1 and activates caspase-9 to initiate the mitochondria-mediated apoptotic pathway (Ulamek-Koziol et al., 2020)

Cells expressing chimera M6 and chimera M8 showed an 8.5 to 9-fold (EC 50 of 60 M and 64 M respectively, compared with 7 M for MRP1 WT) decrease of verapamil + L-BSO sensitivity (Fig