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Description

In Mecp2-null mice, glucocorticoid- and hypoxia-induced transcripts expression was increased in microglia and peritoneal macrophages

focused on developing class A inhibitors using the sildenafil core, together with a wide range of substituents having a terminal hydroxamic acid group (a ZBG essential for HDAC inhibitory activity) and linked to the 5position of the phenyl ring of sildenafil via a carbon, nitrogen, or an oxygen atom [262]