l glutathione oxidised Sigma-Aldrich Glutathione, Oxidized, Free Acid, CAS 27025-41-8, Glutathione, Oxidized, Free Acid, CAS 27025-41-8 Cyclic(γ L-Glutathione oxidized - CAS-Number 27025-41-8

10.1016/j.bbi.2010.12.008 28 BhandariR.KuhadA.KuhadA

doi: 10.3390/ijms22020634

Additionally, patients on medications that affect liver enzymes, particularly those that are substrates, inhibitors, or inducers of cytochrome P450 enzymes, should be monitored for changes in drug efficacy or side effects, as glutathione may influence liver metabolism and thus the pharmacokinetics of these drugs

Given the significant role of these CYP450 isoforms in metabolizing commonly used drugs and endogenous substances, as well as activating procarcinogens into carcinogenic metabolites, the influence of barberry and its active constituent on these enzymes may impact the pharmacokinetics and toxicity profiles of various compounds