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Further, Nrf2 indirectly controls ferroptosis by regulating iron metabolism

sativum is crushed or cut (Iciek et al., 2009

Long-term studies: Long-term follow-up studies are essential to evaluate the sustained impact of ESCM use on human health and to identify any potential long-term side effects or toxicity

Melatonin use is safe and did not show any teratogenic effects in both human and animal (9-10) as well as no toxicity (11) even at very high dose (5-20mg/day)