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The standard HCV diagnostic algorithm (SOC) includes an antibody (AB) test followed by a confirmatory HCV RNA test for those with HCV AB detected

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Like other type I proteins that traverse the lipid bilayer, the lipid-spanning portion of the peptide would be predicted to adopt an alpha-helical secondary conformation, a secondary structure characterized by every amino acid interacting with the 4th amino acid beyond, the so-called i + 4 rule of alpha-helical protein conformations

When turned on, fibroblasts morph into myofibroblasts, which contract wounds and draw edges toward one another