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Reassess for sedation, respiratory depression, medical complications of overdose and/or drug use (aspiration, pulmonary edema, rhabdomyolysis, compartment syndrome, infections)

To avoid coding errors, providers must distinguish between contemporaneous, sequential, and hydrating infusions

Additionally, this route can facilitate faster absorption into the bloodstream via the nasal mucosa, enabling a quicker onset of effects

The initial visit includes intake, baseline bloodwork as clinically indicated, an honest discussion of evidence quality and realistic expectations, and protocol design based on individual goals and clinical profile