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Description

defined PCOS as a gene-dependent ovarian pathology, characterized by the overproduction of androgens and not uniformly represented by the interaction of genetic propensities with other genetic and environmental factors [49]

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It has been observed to regulate approximately 4,000 human genes, essentially shifting the gene expression of aged cells to resemble that of younger, healthier cells

EGF promotes PKM2 O-GlcNAcylation by stimulating O-GlcNAc transferase phosphorylation at Y976 and their subsequent association

2.5 Serum renal function tests Renal function was assessed by measuring serum creatinine, urea, and uric acid, using commercially available diagnostic kit (Randox Laboratories Ltd., Crumlin, County Antrim, UK)