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Imaging was performed with equipment maintained by the Center for Microscopy and Image Analysis (ZMB), University of Zrich (Switzerland)

doi: 10.1016/j.cell.2010.02.027 91 ZellerCDaiWSteeleNLSiddiqAWalleyAJRizzoSet al

Toxicol Res 14(4):tfaf088

The combination of liquid and solid lipids in the core typically allows for higher drug-loading capacity (typically in interstitial space between solid crystalline fatty acid domains), faster release rates, and higher storage stability, all beneficial for IN delivery [114]