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In vitro, Mfn2 reconstitution enhanced mitochondrial membrane potential, mitigated oxidative stress, and promoted fusion-mediated mitochondrial function in cardiomyocytes exposed to high-glucose/HFD conditions, highlighting the regulation of Mfn2 as a promising therapeutic target in DbCM [69]

J Chin Ceram Soc 45(03):327332 Song S, Li X, Ji Y, Lv R, Wu L, Wang H, Cao M, Xu Z (2021) GSH/pH dual-responsive and HA-targeting nano-carriers for effective drug delivery and controlled release[J]