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Glutathione is the body's master antioxidant, essential for cellular protection

Interestingly, the incubation with the antioxidant N-acetylcysteine (NAC) upon treatment with NP4 resulted in reduced levels of apoptosis, suggestive that the cytotoxicity of NP4 is related to intracellular redox homeostasis (Supplementary Fig

Murphy MP, Bayir H, Belousov V, Chang CJ, Davies KJA, Davies MJ et al (2022) Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo