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Filtration through a size exclusion column to remove the excess of reactive keto-enal before the addition of cysteine-containing molecules to the functionalised AON proved to be sufficient, yielding the desired conjugate

In laboratory studies, Cagrilintide has shown potential in modulating satiety pathways and is frequently researched alongside GLP-1 analogues due to its synergistic metabolic activity

Moreover, simplified experimental paradigms often fail to capture the complex, multifactorial nature of human neurodegeneration, including chronic inflammation, metabolic dysfunction, and cumulative injury [569571]

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