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Description

#2 Age-Related Decline Glutathione levels naturally decline with age

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Barski A, Cuddapah S, Cui K, et al

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Additionally, glioblastoma cells enhance iron export via SLC40A1 and buffer mitochondrial iron through Fe-S cluster biosynthesis proteins, such as NFS1 and frataxin, mitigating oxidative stress [34, 35]

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Collectively, these approaches offer novel mechanistic insights and therapeutic avenues for targeting ferroptosis propagation in the AD brain

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