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Figure 2)

The progression from hepatic steatosis to steatohepatitis and cirrhosis is closely related to OS, lipotoxicity, and local inflammation [62,63]

L., Nayak, P

Combination drug studies To quantify the synergistic activity of APR-246 with system x C inhibitors, the GI50 dose of single agents was firstly determined by fitting the Hill equation using Prism 6 software (Graphpad)