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331,332 As a bridge of intercellular communication, classical exosomes have a monolayer structure, which can encapsulate bioactive substances, such as proteins, lipids, DNA, and RNA, in the core and deliver them to effector cells to play specific biological functions (Fig

The effectiveness of dapagliflozin for sleep-disordered breathing among Japanese patients with obesity and type 2 diabetes mellitus

On the other hand, the increase in NO production stimulates the COX-2 expression causing the formation of prostaglandin E2, which is a principal inflammatory mediator [55,56]

Like other lipid A derivatives, MPLA can be enzymatically modified by host phosphatases and lipases, including dephosphorylation and deacylation, which alter lipid A bioactivity (4648)