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Moreover, these alterations may contribute to increased anxiety, reduced self-control, and a greater propensity for impulsive or dominant behaviours, particularly in individuals with pre-existing traits such as poor impulse regulation or antisocial tendencies (59, 60)

Modification of cysteine 179 of IkappaBalpha kinase by nimbolide leads to down-regulation of NF-kappaB-regulated cell survival and proliferative proteins and sensitization of tumor cells to chemotherapeutic agents

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