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The comparison revealed no significant differences in accuracy and precision between the data calculated with and without internal standards

Lipofuscin, a term used to describe lipid peroxidation products in many different cell types, is composed primarily of vitamin A metabolites known as bisretinoid adducts in the RPE cells ( Pathological yellowish extracellular accumulations of lipoproteins, referred to as drusen (Figure 1), form in the macula of the eye during both wet and dry AMD, with their number and size correlating with the advancement of this retinal disease ( The pathological transformations of RPE cells in dry and wet AMD are distinctly different

10.1242/jcs.199570 2 AnestopoulosI.KyriakouS.TragkolaV.ParaskevaidisI.TzikaE.MitsiogianniM.et al (2022)

Frequently studied are metal-based SOD and SOD-catalase mimetic compounds of which several are currently undergoing clinical trials