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Immune complex and LPS/IL-1 stimulation triggers the activation of M2b macrophages leading to increased secretion of pro-inflammatory cytokines such as TNF-, IL-6, and IL-1

RNA concentration and purity were assessed using a NanoDrop spectrophotometer (Thermo Fisher Scientific, USA) by measuring absorbance at 260 and 280 nm

Mtz, a synthetic nitroimidazole is a prodrug and becomes active when reduced in the cytosol of the microorganism to a toxic metabolite

Levels return to normal when drinking is stopped, but if high levels of GGT persist, it is likely that some liver damage has been sustained or that the patient is still drinking