intracellular glutathione detection using mno2-nanosheet-modified Upconversion Nanoparticles Highly fluorescent carbon dots-MnO2 nanosheets

If an abnormally high cumulative doses are administered, or the patient has low plasma pseudocholinesterase activity, then Phase I block can progress into Phase II block due to the inclusion of additional mechanisms that come into play when high synaptic levels of succinylcholine are achieved

doi: 10.1016/j.neulet.2016.12.033 9 BetlazarC.MiddletonR

Single and multitarget systems for drug delivery and detection: up-to-date strategies for brain disorders

The so-called nerve gases and many substances used in insecticides have been shown to act by combining with a residue of serine in the active site of acetylcholine esterase, inhibiting the enzyme completely