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To compare AfCycDesign-generated sequences to sequences designed by ProteinMPNN, we we also designed sequences of 22,182 10 residue hallucinated backbones using ProteinMPNN 32 and compared the pLDDT of peptides designed by both methods (Supplementary Fig

Fenton, J

A good example of this is given by flutamide, an antiandrogen used in the treatment of prostatic carcinoma, which undergoes substantial metabolism in vivo with hydrolysis of the amide bond liberating 3-trifluoromethyl-4-nitroaniline