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Studies found that during acute ischemic stroke, the imbalance between oxidants and antioxidants could further disrupt monoamine reactions by reducing dopamine and serotonin concentrations

Zhu et al., 2020), regulating ferroptosis may be a useful strategy for targeting the drug-resistant tumor cells (Yang et al., 2017

Based on these arguments, it was concluded that symptomatic treatment with NSAIDs for non-severe symptoms (fever, pain, or myalgia) is not to be recommended