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SUBCELLULAR LOCALIZATION OF AsGGT1, AsGGT2, AND AsGGT3 The probable subcellular localization of AsGGT1, AsGGT2, and AsGGT3 was computationally analyzed using the program TargetP v1.1 3 and WoLF PSORT 4

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New York, 369-379

In this study, we used cryogenic electron microscopy (cryo-EM) to determine structures of Cagri bound to Gs-coupled, active, AMY 1 R, AMY 2 R, AMY 3 R and CTR and compared the mode of interaction of Cagri and the associated dynamics of the Cagri-bound receptor complexes with previously reported cryo-EM structures and dynamics of receptors bound to rat amylin (rAmy, all receptor subtypes), sCT (CTR, AMY 1 R, AMY 2 R) 15 or recently developed amylin-based peptides (CTR and/or AMY 3 R) 16