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Commenters expressed their views on the benefits of ASP, including that ASP is updated quarterly, is more consistent, transparent, and aligned with payment for many other Part B drugs

A typical assumption for the expected body weight for participants lost to follow up would be that these participants, on average, weigh the same at the end of the trial as comparable participants (by age, sex, occupation, family structure, etc.) who discontinued treatment at a similar time, but remained in the trial and thus had a final weight measurement