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Consistent with the hypothesis that GS dysfunction in astrocytes impairs glutamatergic homeostasis and induces depression-like phenotypes, GS cKO mice exhibited significant anxiety, helplessness, and anhedonia in the OFT, TST, and SPT, respectively (Fig

And 40 minutes later, she had a very satisfying BM

Tofacitinib also significantly inhibits IL-22-induced CXCL1 and CXCL5 expression in human colonic tissues, suggesting that targeting the IL-22/CXC chemokine axis through JAK/STAT inhibition may be a viable therapeutic strategy

VYVANSE is not approved for use and is not recommended in pediatric patients below 6 years of age [see Use in Specific Populations (8.4)]