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Unlike many drugs that simply block or force a pathway, these peptides were designed as bioregulators. They are analogs of molecules naturally found in the body that are based on an immune peptide called tuftsin, which is derived from a hormone fragment known as ACTH

Arendt-Nielsen L, Morlion B, Perrot S, Dahan A, Dickenson A, Kress HG, et al

Similar content being viewed by others Introduction Approximately one in five cases of familial amyotrophic lateral sclerosis (fALS) is due to naturally occurring mutations in the gene encoding superoxide dismutase 1 (SOD1) 1

Several of the DEGs were TF genes, including Klf4 and Klf5 , (Extended Data Fig