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Thereby, as a part of the counteraction of the symptoms of severe vascular and multiorgan failure syndrome, and of progressing Virchow counteraction, there was counteraction of severe lesions of the brain, heart, lung, liver, kidney and gastrointestinal system, progressing thrombosis, in peripheral and central arteries and veins [5,6,66,71,72,73,74,75,76,77,78,79,80,81,82], intracranial (superior sagittal sinus), portal and caval hypertension, and aortal hypotension, all of which were attenuated or eliminated

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Animal model research in the published literature has explored dermal and connective tissue applications using topical or localized administration protocols in rodent models

73,74 Combined with ICB or innate agonists, ferroptosis improves effector responses in cold or apoptosis-resistant tumors