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Shah K, Gagliano T, Garland L, OHanlon T, Bortolotti D, Gentili V, et al

L-carnitine is primarily responsible for the transport of long-chain fatty acids into the mitochondria, the powerhouse of cells, where they are oxidised to produce energy

It also supports nerve regeneration and reduces oxidative stress two mechanisms thought to underlie its benefits for diabetic neuropathy.48 Randomized trials have shown that taking 1,0002,000mg of ALCAR daily may help reduce pain, improve vibration perception, and enhance nerve conduction in people with diabetic neuropathy especially when treatment begins early.49 Vibration perception refers to the ability to sense low-frequency vibrations, such as those from tuning forks a key part of nerve function often tested in clinical exams to assess sensory loss in the feet and legs

J Pain Res 13:34573465