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This impairment was evidence both when glucose was the primary fuel source, and when fatty acids were used alongside the uncoupler carbonyl-p-trifluoromethoxyphenylhydrazone, which bypasses the respiratory control mechanisms

The search terms used included GLP-1 agonists, Glucagon-Like Peptide-1 Receptor Agonists, semaglutide, Ozempic, Wegovy, liraglutide, bone health, orthopedic surgery, arthroplasty, post-operative complications, complications, bone health, bone strength, osteogenesis, and bone metabolism. To ensure the relevance and quality of the studies, we established specific inclusion and exclusion criteria

Freitas WR Jr, Oliveira LVF, Perez EA, et al

Therefore future efforts in neuroprotective strategies should emphasize the mitochondrial protection in astrocytes