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In vitro and animal studies suggests that GSH depletion plays an important role in OS-mediated neuronal death and is implicated in neuronal loss in several neurodegenerative diseases, such as Parkinsons disease [16], AD [17], and amyotrophic lateral sclerosis [12], making it a potential therapeutic target to prevent or reduce neurodegeneration

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J Psychiatr Ment Health Nurs 15:424434 Tardiolo G, Bramanti P, Mazzon E (2018) Overview on the effects of N-Acetylcysteine in neurodegenerative diseases