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Such heterogeneity complicates the development of universally effective therapies and underscores the need for personalized approaches, which currently face limitations due to an incomplete understanding of these individual determinants (164)

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Proc Natl Acad Sci USA 94:1110211107 Takahashi H, Watanabe-Takahashi A, Smith FW, Blake-Kalff M, Hawkesford MJ, Saito K (2000) The roles of three functional sulphate transporters involved in uptake and translocation of sulphate in Arabidopsis thaliana