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Description

Immunomodulation by vitamin B12: augmentation of CD8+ T lymphocytes and natural killer (NK) cell activity in vitamin B12-deficient patients by methyl-B12 treatment

The influence of MTHFR on psychiatric diseases is mainly through reduction of MTHFR activity which results in elevation of homocysteine, reduction of DNA methylation-dependent methyl donor, finally induces hypomethylation, and then active disease-related genes

With larger than recommended doses, a person might experience nausea, vomiting, diarrhea, stomach painsimilar abdominal and intestinal issues that can occur with high doses of BCAAs, Creatine or Beta Alanine, etc