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10.1016/j.actbio.2021.03.030 39 HwangJ

The cumulative effect is allergic inflammation, often systemic

Plant Cell 6 (2), 251264

Although HCU is a rare genetic enzymatic disorder, with global prevalence estimates of 1 in 300,000 individuals, its prevalence rates vary considerably across different regions due to factors such as genetic mutations and consanguinity (4)