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Human exposure to heavy metals occurs via various pathways, including inhalation of air/dust particles, ingesting contaminated water or soil, or through the food chain

doi: 10.1016/j.chembiol.2020.03.016 59 MorrisGBortolasciCCPuriBKOliveLMarxWO'NeilAet al

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In this process, GSH is constantly oxidized to GSSG by the enzyme glutathione peroxidase.To maintain the intracellular redox balance, GSH is replenished through the reduction GSSG by glutathione reductase enzyme