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In vivo antitumor assay All animal operations followed the guidelines of the Institutional Animal Care and Use Committee (IACUC) of the Animal Experiment Center of the Chinese University of Hong Kong (Shenzhen, China, protocol number, CUHKSZ-AE2022004)

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Iron exchange in the mitochondria is mediated by DMT-1 and classical mitoferrins (Mfrn) 1 and 2 [38], which are incorporated into the electron transport chain and produce ATP under the stimulation of glucose