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Fibroblast cultures are commonly used to measure transcriptional responses involving matrix-associated proteins, growth signaling regulators, and stress-response pathways

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Kyoto Encyclopedia of Genes and Genomes (KEGG)-based analysis showed that the differentially expressed metabolites were involved in arachidonic acid metabolism, the glycerophospholipid pathway, and inflammatory mediator regulation of Transient receptor potential channel (TRP) channels, suggesting that allicin may change the metabolism in the peri-infarct cortex, especially arachidonic acid metabolism (Fig

Likewise in our previous studies of glaucoma, we have observed metabolic deficiency in the DBA/2J optic nerve that coincides with an early period of degeneration [69]