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Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response

Beyond its role as a glutathione precursor, NAC has unique benefits, such as: Respiratory support : NAC helps thin mucus and improve lung function Neuroprotection : It influences glutamate regulation in the brain, which may support mood and cognitive health Detoxification : NAC directly binds to certain toxins, making them less harmful Antioxidant activity : NAC can directly scavenge free radicals, though less potently than glutathione itself Key Distinction In short: Glutathione = the end product , the bodys main antioxidant and detox molecule

Waring RH, Emery P