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116 Diagnostic approaches for CAN include HRV tests such as the deep breathing test, valsalva maneuver, and orthostatic testing, along with ambulatory blood pressure monitoring to identify irregular circadian blood pressure patterns

This cascade of oxidative damage to proteins, lipids, and DNA highlights the interconnected pathways through which NO affects neural integrity ( 6.2.2 Excitotoxicity NO acts as a noncompetitive inhibitor of NMDAR, disrupting their regulatory role in synaptic plasticity, memory, and learning (Wu et al., 2021)

While the anti-aging implications have not been studied directly in humans, the mechanistic pathway is well-established and suggests potential benefits for anti-aging applications