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Evidence indicates that imbalances in antioxidant enzymes such as superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase correlate with disease progression, while polymorphisms in GST, superoxide dismutase, CAT, and HO-1 genes may modify susceptibility and outcomes

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Demyelination causes a multitude of neurological symptoms, including loss of coordination of movement, ataxia, visual impairments, psychiatric abnormalities such as depression, and cognitive decline (Preiningerova et al., 2022)