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In accounting for these findings, our own molecular modelling of the known sites for 4-HNE adduction within tubulin indicate that this form of modification is likely to cause both changes in the tertiary structure of the protein and importantly, alter the surface characteristics of the tubulin monomers

Immunohistochemistry: 5-20g/mL

Distinct mechanisms govern populations of myeloid-derived suppressor cells in chronic viral infection and cancer

Alfonso Pierola A, Montalban-Bravo G, Chamseddine AN, Takahashi K, Wang F, Xingzhi S, Jabbour EJ, Kadia TM, Ravandi F, Cortes JE, DiNardo CD, Daver NG, Borthakur G , Pemmaraju N, Konopleva M, Bueso-Ramos CE, Patel K, Futreal A, Pierce S, Kantarjian HM, Garcia-Manero G