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Consistent with this, NNMT knockdown increased 2-DG resistance in PANC-1 cells

Dray, "B12 deficiency can cause graying of the hair as well as hyperpigmentation over your knuckles and your feet." Vitamin B12 is essential for red blood cell production, nerve health, and DNA synthesis, all of which play a role in healthy hair follicle function and pigment production

Vitamin D deficiency is strongly associated with myofascial pain syndrome and chronic pain muscle spasms, particularly in populations with limited sun exposure

The divergent roles of dietary saturated and monounsaturated fatty acids on nerve function in murine models of obesity