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Tnnies E, Trushina E (2017) Oxidative stress, synaptic dysfunction, and alzheimers disease

Zhang Y, Shi Y, Lin J, Li X, Yang B, Zhou J

During the reproductive years, ovaries are palpable, but following menopause, they undergo significant atrophy and shrink considerably

Moreover, the infected modeled animals should develop clinical features/morbidity (pathophysiology and clinical manifestations, i.e., signs and symptoms) that resemble human disease and the symptom severity should correlate with the viral load and demographic conditions in human (elderly and immunocompromised subjects are vulnerable to severe disease and mortality)