glutathione midpoint potential The System: A Journey from Cyanobacteria to Higher Eukaryotes Scheme of glutaredoxin(GRX)-dependent oxidative signaling

During oxidative stress, modifications in cysteine residues on Keap1 release Nrf2, allowing it to translocate into the nucleus, bind to AREs in target genes, and initiate transcription of essential antioxidant genes 67

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3.5 The induction of GPX activity in plants provides protection against biotic stress The determination of antioxidant enzyme activity is often used to evaluate responses of susceptible and/or resistant plants against pathogens