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Ziegler tasked with formulating a superior steroid to testosterone so the American Olympic team could defeat the USSR, which was known to be injecting testosterone

The skin and mucous membranes are often bypassed, so that pallor, abnormal pigmentation, icterus, spider nevi, petechiae, purpura, angiomas, ulcerations, palmar erythema, coarseness of hair, puffiness of the face, thinning of the lateral aspects of the eyebrows, and nail defects are missed in the rush to examine the heart and the lungs (Maakaron & Besa, 2021)

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