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Science advances through critical verification rather than by repeatedly affirming findings within the same research group, a team of scientists in Poland wrote in response to Sikirics BPC157 claims

Together, these peptides may support recovery, movement, skin health, collagen support, and overall wellness goals when used under provider supervision

What is missing There is no published human pharmacokinetic study of subcutaneous AOD-9604, no published human topical or intranasal exposure data, no Phase 3 efficacy trial, no long-term safety data beyond 24 weeks, and no published human cartilage or joint outcome data

Nevertheless, the efficacy of these interventions necessitates validation through multicenter randomized controlled clinical trials