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161 ATG4 plays a significant role in apoptosis, as ATG4 may shift cells from survival to apoptosis when autophagy is inhibited

Molecules 27 , 1899 (2022)

Chen S, Vaghchhipawala Z, Li W, Asard H, Dickman MB (2004) Tomato phospholipid hydroperoxide glutathione peroxidase inhibits cell death induced by Bax and oxidative stresses in yeast and plants

Compared to HGPS, the onset of Werner syndrome is slightly slower, in which the pathology accompanies with Werner syndrome resembles a premature aging