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In human embryonic stem cells, CHAC2 is highly enriched and is crucial for maintaining self-renewal capacity

Moreover, Lip-1 reduced microglial activation and the secretion of pro-inflammatory cytokines such as IL-6 and TNF-, while mitigating oxidative stress, lipid peroxidation, mitochondrial damage and neuronal injury following LPS exposure

The effect of cumulative standardized statin dose and duration showed a significant interaction with age (interaction: p =0.0005 and p 10-fold variation of cirrhosis incidence between the bottom quintiles (1-2) and top quintile (5) of RF model risk (Table)

Maintains mitochondrial function and reduces oxidative stress